HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab05658(RDBP antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer using FNab05658(RDBP antibody) at dilution of 1:100
Background
The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6.